Abstract Background Treatment of non-small cell lung cancer with novel targeted therapies is a major unmet clinical need.Alternative splicing is a mechanism which generates diverse protein products and is of functional relevance in cancer.Results In this study, a genome-wide analysis of the alteration of splicing patterns between lung cancer and no
At the end of the 18th - early 19th centuries, the trade relations between the Principality of Moldova and the Russian Empire were determined by a number of new Connetix features that represent a new stage in the development of economic relations between the countries.Intensification of trade relations between the Principality of Moldova and Russia
This paper studies the changes of ecological efficiency (eco-efficiency) boom in China.Firstly, based on the improvement of the three-stage slack-based model (SBM), a hybrid chain network model is used to clarify the internal development structure of eco-efficiency.Then, Taking eco-efficiency as the benchmark indicator, the boom warning indicators
In cartography, generalization is a key process used to simplify complex geographic information, making it suitable for display at different scales while maintaining its essential meaning.When representing high-density road networks on a fixed screen area, overcrowding and loss of clarity often occur.To solve these problems, a road selection operat